Pulling on a cytokine

Aparna Sreenivasan

doi:10.1083/JCB1655ITI1

Pulling on a cytokine

Department of Biology and Chemistry

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Cell Biology
Volume	165
DOIs	https://doi.org/10.1083/JCB1655ITI1
State	Published - Jun 2004

Disciplines

Biology
Cell Biology

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10.1083/JCB1655ITI1License: Unspecified

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@article{64e45a5f4326443389f5cad6b684043b,

title = "Pulling on a cytokine",

author = "Aparna Sreenivasan",

note = "Thus, the function of LTBP may be in part to anchor latent TGF-β in the ECM. But for activation, the authors speculate that this anchoring also gives the cell something to pull against. Only when integrin-mediated pulling meets resistance (because the integrin on the cell binds to TGF-β, and the TGF-β binds to the ECM-anchored LTBP) would the pro-domain be released.",

year = "2004",

month = jun,

doi = "10.1083/JCB1655ITI1",

language = "American English",

volume = "165",

journal = "Journal of Cell Biology",

}

TY - JOUR

T1 - Pulling on a cytokine

AU - Sreenivasan, Aparna

N1 - Thus, the function of LTBP may be in part to anchor latent TGF-β in the ECM. But for activation, the authors speculate that this anchoring also gives the cell something to pull against. Only when integrin-mediated pulling meets resistance (because the integrin on the cell binds to TGF-β, and the TGF-β binds to the ECM-anchored LTBP) would the pro-domain be released.

PY - 2004/6

Y1 - 2004/6

UR - https://doi.org/10.1083/jcb1655iti1

U2 - 10.1083/JCB1655ITI1

DO - 10.1083/JCB1655ITI1

M3 - Article

VL - 165

JO - Journal of Cell Biology

JF - Journal of Cell Biology

ER -

Pulling on a cytokine

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